Optical Coherence Tomography Angiography in Uveitic Glaucoma - A Pilot Study

Ocul Immunol Inflamm. 2021 Nov 17;29(7-8):1410-1416. doi: 10.1080/09273948.2020.1745246. Epub 2020 Nov 13.


Purpose: To compare vessel density (VD) as measured by optical coherence tomography angiography (OCTA), in uveitic eyes with secondary glaucoma (UG) with VD in uveitic eyes without glaucoma (UV), eyes with primary open-angle glaucoma (POAG), and healthy eyes (HY).Methods: VD was measured at the following segmentation areas: radial peripapillary capillaries, superficial (SL) and deep vascular plexus (DL) and choroid.Results: The majority of the measured papillary areas showed significantly lower VD in the UG group than in the HY group. In macular area, in the superficial vascular plexus wholeVD was significantly lower than in the healthy group, as well as in four other quadrants. In DL no significant differences could be found. At choroidal level, the VD of UG group were significantly lower in two quadrants than in UV group.Conclusions: OCTA can be used to detect differences in VD in papillary and macular region of uveitis glaucoma eyes.

Keywords: FAZ; OCT angiography; Vessel density; blood flow; uveitis.

MeSH terms

  • Adult
  • Aged
  • Choroid / blood supply*
  • Computed Tomography Angiography*
  • Female
  • Glaucoma, Open-Angle / diagnostic imaging*
  • Glaucoma, Open-Angle / physiopathology
  • Gonioscopy
  • Humans
  • Male
  • Middle Aged
  • Nerve Fibers / pathology
  • Optic Disk / blood supply*
  • Pilot Projects
  • Prospective Studies
  • Retinal Ganglion Cells / pathology
  • Retinal Vessels / diagnostic imaging*
  • Tomography, Optical Coherence*
  • Uveitis / diagnostic imaging*
  • Uveitis / physiopathology
  • Visual Acuity / physiology