Oncologic Emergencies: Traditional and Contemporary

Crit Care Clin. 2021 Jan;37(1):85-103. doi: 10.1016/j.ccc.2020.08.004. Epub 2020 Oct 29.


The recognition and management of oncologic emergencies are becoming increasingly relevant in the intensive care unit, particularly in the era of novel biologic therapies. Early recognition and multidisciplinary collaboration are essential to improving patient outcomes. This article discusses aspects of diagnosis and management for important malignancy-associated emergencies.

Keywords: Cytokine release syndrome; Hyperleukocytosis and leukostasis; Immune-related adverse events; Malignant pericardial effusion; Metastatic spinal cord compression; Superior vena cava syndrome; Syndrome of inappropriate antidiuretic hormone; Tumor lysis syndrome.

Publication types

  • Review

MeSH terms

  • Emergencies*
  • Humans
  • Neoplasms* / complications
  • Neoplasms* / therapy