COVID-19 pandemic and antiretrovirals (ARV) availability in Nigeria: recommendations to prevent shortages

Pan Afr Med J. 2020 Aug 24;35(Suppl 2):149. doi: 10.11604/pamj.supp.2020.35.149.25639. eCollection 2020.

Abstract

HIV/AIDS is an infectious disease that has claimed the lives of millions of people worldwide. Currently, there is no vaccine that has been developed in a bid to fight this deadly infection, however, antiretrovirals (ARVs), which are drugs used in the treatment of HIV infection are routinely prescribed to infected persons. They act via several mechanisms of action to reduce the severity of infection and rate of infectivity of the virus by decreasing the viral load while increasing CD4 counts. COVID-19 pandemic has resulted in unprecedented events affecting almost all areas of humans' life including availability of medicines and other consumables. This paper analyses the availability of ARVs during COVID-19 era and offered recommendations to be adopted in order to prevent shortages.

Keywords: COVID-19; HIV; antiretroviral; drug shortage.

MeSH terms

  • Anti-HIV Agents / economics
  • Anti-HIV Agents / supply & distribution
  • Anti-HIV Agents / therapeutic use
  • Anti-Retroviral Agents / economics
  • Anti-Retroviral Agents / supply & distribution
  • Anti-Retroviral Agents / therapeutic use*
  • Antiretroviral Therapy, Highly Active / economics
  • Betacoronavirus
  • COVID-19
  • Coronavirus Infections / drug therapy*
  • Coronavirus Infections / economics
  • Coronavirus Infections / epidemiology
  • Developing Countries
  • Drug Costs / trends
  • Drug Industry
  • Drug Repositioning*
  • HIV Infections / drug therapy*
  • HIV Infections / economics
  • HIV Infections / epidemiology
  • Health Services Accessibility
  • Humans
  • Insurance, Pharmaceutical Services
  • Medication Adherence
  • Nigeria / epidemiology
  • Pandemics* / economics
  • Pneumonia, Viral / drug therapy*
  • Pneumonia, Viral / economics
  • Pneumonia, Viral / epidemiology
  • SARS-CoV-2
  • Viral Load / drug effects

Substances

  • Anti-HIV Agents
  • Anti-Retroviral Agents