The Role of Noncoding RNAs in B-Cell Lymphoma

Jingwen Li; Jing Zou; Xiaoyue Wan; Chunyan Sun; Fei Peng; Zhangbo Chu; Yu Hu

doi:10.3389/fonc.2020.577890

The Role of Noncoding RNAs in B-Cell Lymphoma

Front Oncol. 2020 Oct 23:10:577890. doi: 10.3389/fonc.2020.577890. eCollection 2020.

Authors

Jingwen Li¹, Jing Zou¹, Xiaoyue Wan¹, Chunyan Sun^{1

2}, Fei Peng¹, Zhangbo Chu¹, Yu Hu^{1

2}

Affiliations

¹ Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
² Collaborative Innovation Center of Hematology, Huazhong University of Science and Technology, Wuhan, China.

Abstract

In recent years, emerging evidence has suggested that noncoding RNAs (ncRNAs) participate in nearly every aspect of biological processes and play a crucial role in the genesis and progression of numerous tumors, including B-cell lymphoma. The exploration of ncRNA dysregulations and their functions in B-cell lymphoma provides new insights into lymphoma pathogenesis and is essential for indicating future clinical trials and optimizing the diagnostic and therapeutic strategies. In this review, we summarize the role of ncRNAs in B-cell lymphoma and discuss their potential in clinical applications.

Keywords: B cell development; B-cell lymphoma; circular RNA; long-noncoding RNA; microRNA.

Publication types

Review