Woodchuck hepatitis post-transcriptional regulatory element improves transgene expression and stability mediated by episomal vectors in CHO-K1 cells

Acta Biochim Biophys Sin (Shanghai). 2020 Dec 11;52(11):1285-1288. doi: 10.1093/abbs/gmaa105.

Authors

Xiaoyin Wang^{1

2}, Weili Zhang¹, Yanlong Jia³, Meng Wang², Dandan Yi^{1

2}, Tian-Yun Wang^{1

2}

Affiliations

¹ Department of Biochemistry and Molecular Biology, Xinxiang Medical University, Xinxiang 453003, China.
² International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang 453003, China.
³ Pharmacy College, Xinxiang Medical University, Xinxiang 453003, China.

PMID: 33196825
DOI: 10.1093/abbs/gmaa105

No abstract available

MeSH terms

Animals
CHO Cells
Cricetulus
Gene Expression*
Genetic Vectors / genetics*
Hepatitis B Virus, Woodchuck / genetics*
Plasmids / metabolism*
Response Elements*
Transgenes*