[Effect of diltiazem on blood cyclosporin levels]

Klin Wochenschr. 1987 Nov 16;65(22):1101-3. doi: 10.1007/BF01736117.
[Article in German]

Abstract

The simultaneous administration of the calcium channel blocker diltiazem and cyclosporin results in a significant increase of RIA cyclosporin blood levels. The HPLC cyclosporin levels are not influenced.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • English Abstract

MeSH terms

  • Acute Kidney Injury / prevention & control*
  • Chromatography, High Pressure Liquid
  • Cyclosporins / pharmacokinetics*
  • Cyclosporins / therapeutic use*
  • Diltiazem / therapeutic use*
  • Drug Therapy, Combination
  • Graft Rejection / drug effects
  • Humans
  • Kidney Transplantation*
  • Postoperative Complications / prevention & control*
  • Radioimmunoassay

Substances

  • Cyclosporins
  • Diltiazem