Cardiovascular Contribution to Maternal Mortality

Cardiol Clin. 2021 Feb;39(1):1-5. doi: 10.1016/j.ccl.2020.09.001. Epub 2020 Nov 2.


The United States is the only industrialized nation with an increasing maternal mortality. Many factors contribute to this worrisome US trend; among them, social and demographic factors, and congenital and acquired cardiac conditions. Cardiovascular disease is the leading cause of maternal mortality, and adverse outcomes related to cardiovascular disease disproportionately affect black and Hispanic mothers. This article addresses knowledge gaps related to the treatment of heart disease in pregnancy, initiatives to address these gaps, and guidelines and best practices surrounding the care of women affected by cardiovascular disease and their babies affected by cardiovascular disease.

Keywords: Cardio-obstetrics; Cardiovascular; Maternal mortality.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases* / epidemiology
  • Cardiovascular Diseases* / therapy
  • Female
  • Humans
  • Maternal Health Services / standards*
  • Maternal Mortality* / ethnology
  • Maternal Mortality* / trends
  • Practice Guidelines as Topic
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / epidemiology
  • Pregnancy Complications, Cardiovascular / therapy
  • Professional Practice Gaps / ethnology
  • Social Determinants of Health
  • United States / epidemiology