Advances in the Treatment of Multiple Sclerosis

Neurol Clin. 2021 Feb;39(1):21-33. doi: 10.1016/j.ncl.2020.09.002. Epub 2020 Nov 7.

Abstract

Multiple sclerosis is a relatively common, immune-mediated neurologic disease of the central nervous system that can cause significant disability and lead to reduced quality of life. There are several currently approved disease-modifying therapies, and more in the pipeline being developed and tested. As the field learns more about the pathophysiology and natural course of the disease, the treatment approaches are also being investigated. This article reviews data on available treatments along with a discussion of future treatment targets under investigation.

Keywords: Disease-modifying treatment; Multiple sclerosis; Neuroprotection therapies; Remyelination therapies; Treatment approaches.

Publication types

  • Review

MeSH terms

  • Humans
  • Immunologic Factors / therapeutic use*
  • Multiple Sclerosis / drug therapy*
  • Neuroprotective Agents / therapeutic use*

Substances

  • Immunologic Factors
  • Neuroprotective Agents