The Naming of Memory T-Cell Subsets

Cold Spring Harb Perspect Biol. 2021 Jan 4;13(1):a037788. doi: 10.1101/cshperspect.a037788.

Abstract

With ever-improving methods of cell characterization, the field of immunology has enjoyed unprecedented opportunities to resolve distinctions between lymphocyte populations. However, this has led to a proliferation of "subset" designations that threatens to complicate and confuse clear identification of populations that share critical functional traits. This article discusses some of the challenges associated with a uniform approach to assigning subset designations to memory T-cell populations.

Publication types

  • Review

MeSH terms

  • Animals
  • CD4-Positive T-Lymphocytes / immunology*
  • Cell Differentiation
  • Homeostasis
  • Humans
  • Immunologic Memory*
  • Lymphocyte Activation / immunology*
  • Mice
  • Phenotype
  • T-Lymphocyte Subsets / immunology*
  • T-Lymphocytes / cytology