Cancer-related cognitive impairment in patients with non-central nervous system malignancies: an overview for oncology providers from the MASCC Neurological Complications Study Group

Support Care Cancer. 2021 Jun;29(6):2821-2840. doi: 10.1007/s00520-020-05860-9. Epub 2020 Nov 24.

Abstract

Cancer-related cognitive impairment (CRCI) is commonly experienced by individuals with non-central nervous system cancers throughout the disease and treatment trajectory. CRCI can have a substantial impact on the functional ability and quality of life of patients and their families. To mitigate the impact, oncology providers must know how to identify, assess, and educate patients and caregivers. The objective of this review is to provide oncology clinicians with an overview of CRCI in the context of adults with non-central nervous system cancers, with a particular focus on current approaches in its identification, assessment, and management.

Keywords: CRCI; Cancer; Cancer-related cognitive impairment; Chemotherapy-related cognitive impairment; Cognition; Cognitive functioning.

Publication types

  • Review

MeSH terms

  • Cognitive Dysfunction / etiology*
  • Humans
  • Neoplasms / complications*