A scientometric analysis of research publications on male infertility and assisted reproductive technology

Andrologia. 2021 Feb;53(1):e13842. doi: 10.1111/and.13842. Epub 2020 Nov 24.


Assisted reproductive technologies (ART) are considered as one of the primary management options to address severe male factor infertility. The purpose of this study was to identify the research trends in the field of male infertility and ART over the past 20 years (2000-2019) by analysing scientometric data (the number of publications per year, authors, author affiliations, journals, countries, type of documents, subject area and number of citations) retrieved using the Scopus database. We used VOS viewer software to generate a network map on international collaborations as well as a heat map of the top scientists in this field. Our results revealed a total of 2,148 publications during this period with Cleveland Clinic Foundation contributing the most (n = 69). The current scientometric analysis showed that the research trend on ART has been stable over the past two decades. Further in-depth analysis revealed that density gradient centrifugation (46%) and intracytoplasmic sperm injection (59.2%) are the most reported techniques for sperm separation and ART, respectively. Additionally, azoospermia was the most studied clinical scenario (60.6%), with majority of articles reporting pregnancy rate (47.25%) as the primary reproductive outcome for ART. This study provides insight into the current focus of research in the area of male infertility and ART as well as the areas that require further research in future.

Keywords: assisted reproductive technique; male infertility; publications; research trend; scientometric analysis.

MeSH terms

  • Female
  • Humans
  • Infertility, Male* / therapy
  • Male
  • Pregnancy
  • Pregnancy Rate
  • Reproductive Techniques, Assisted*
  • Sperm Injections, Intracytoplasmic
  • Spermatozoa