Functional Magnetic Resonance Imaging-Guided Personalization of Transcranial Magnetic Stimulation Treatment for Depression

JAMA Psychiatry. 2021 Mar 1;78(3):337-339. doi: 10.1001/jamapsychiatry.2020.3794.


This study assesses whether treatment response for depression could be improved via a single one-site-fits-all dorsolateral prefrontal cortex target, representing the group average optimal site of subgenual cingulate cortex functional connectivity, or whether target site personalization is necessary.

Publication types

  • Clinical Trial
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Brain Mapping*
  • Depressive Disorder, Major / diagnostic imaging*
  • Depressive Disorder, Major / therapy*
  • Dorsolateral Prefrontal Cortex*
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Outcome and Process Assessment, Health Care
  • Transcranial Magnetic Stimulation / methods
  • Transcranial Magnetic Stimulation / standards*

Associated data

  • ANZCTR/ACTRN12610001071011