Vitamins A, B, C, and D: A Short Review for the Dermatologist

Altern Ther Health Med. 2021 Jul;27(4):41-49.


Background: Vitamins and their derivatives are used extensively in the field of dermatology to treat a range of conditions, both benign and malignant. Additionally, over the past decade, vitamin supplements have been heavily advertised for improving overall health. Due to the widespread use of vitamins and their derivatives for dermatologic conditions, a comprehensive review of the evidence is needed.

Objective: Here we review several of the well-established uses of vitamins A, B, C, and D in the management of dermatologic conditions ranging from acne vulgaris to malignant melanoma. Additionally, we examine the dermatologic consequences of both deficiency and excess of vitamins A, B, C, and D. Finally, we delve into newer applications for these vitamins and evaluate the evidence behind them.

Conclusion: Vitamins, in both topical and oral forms, play a key role in treating many dermatologic conditions. Some of the newer applications of vitamins, such as the use of vitamin B3 for non-melanoma skin cancer prevention, vitamin B6 for prevention of chemotherapy-induced alopecia, and vitamin C as an adjuvant treatment for malignant melanoma, appear promising. Further data is needed to validate these findings. Additionally, many people use vitamin B7 for hair, skin, and nail health. There is evidence that supports vitamin B7 supplementation in patients with uncombable hair syndrome, brittle nail syndrome, and seborrheic dermatitis. Some studies Some studies have also demonstrated a benefit in healthy individuals, although other studies have shown a neutral effect. Further randomized controlled trials are needed. Likewise, the use of vitamin D for the treatment of atopic dermatitis has conflicting results and requires further investigation. New research continues to emerge regarding vitamin supplementation, and it is an important topic for dermatologists.

Publication types

  • Review

MeSH terms

  • Ascorbic Acid
  • Dermatologists*
  • Dietary Supplements
  • Humans
  • Vitamin A / therapeutic use
  • Vitamin D
  • Vitamins* / therapeutic use


  • Vitamins
  • Vitamin A
  • Vitamin D
  • Ascorbic Acid