Laws limiting prescribing and dispensing of opioids in the United States, 1989-2019

Addiction. 2021 Jul;116(7):1817-1827. doi: 10.1111/add.15359. Epub 2021 Jan 18.

Abstract

Background and aims: Opioid overdose is a public health emergency in the United States. In an attempt to reduce potentially inappropriate opioid prescribing, many US states have adopted legal restrictions on the ability of medical professionals to prescribe or dispense opioids for pain. This review describes the major elements of relevant US state laws and the ways in which they have changed over time.

Methods: Systematic legal review in which two trained legal researchers collected and reviewed all US state laws that limit the amount or duration of opioids that medical professionals may prescribe or dispense for pain. These laws were then coded on a set of pre-selected measures, including when the law was enacted, dosage and duration limits imposed, circumstances in which the restrictions do not apply and whether additional requirements or restrictions apply to prescriptions issued to minors.

Results: The number of US states with opioid limitation laws increased from 10 in 2016 to 39 by the end of 2019. The provisions of these laws vary between states and have shifted within states over time. At the end of 2019 the modal duration limit was 7 days, with a range of 3 to 31. Fourteen states imposed limits on the dosage of opioids that can be prescribed, ranging from 30 morphine milligram equivalents (MME) to a 120 MME daily maximum. In 16 states, different limits apply to prescriptions issued to minors.

Conclusions: The number of US states with opioid limitation laws nearly quadrupled between 2016 and 2019, with a great amount of heterogeneity between state restrictions and changes over time.

Keywords: Law; opioids; overdose; pain; policy; prescribing.

Publication types

  • Review

MeSH terms

  • Analgesics, Opioid* / therapeutic use
  • Drug Prescriptions
  • Humans
  • Opiate Overdose*
  • Practice Patterns, Physicians'
  • United States

Substances

  • Analgesics, Opioid