Management guideline for Werner syndrome 2020 1. Dyslipidemia and fatty liver associated with Werner syndrome

Kazuhisa Tsukamoto; Minoru Takemoto; Yoshitaka Kubota; Toshibumi Taniguchi; Sei-Ichiro Motegi; Akira Taniguchi; Hironori Nakagami; Yoshiro Maezawa; Masaya Koshizaka; Hisaya Kato; Seijiro Mori; Masafumi Kuzuya; Koutaro Yokote

doi:10.1111/ggi.14095

Management guideline for Werner syndrome 2020 1. Dyslipidemia and fatty liver associated with Werner syndrome

Geriatr Gerontol Int. 2021 Feb;21(2):133-138. doi: 10.1111/ggi.14095. Epub 2020 Dec 1.

Authors

Affiliations

¹ Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan.
² Department of Diabetes, Metabolism and Endocrinology, School of Medicine, International University of Health and Welfare, Chiba, Japan.
³ Department of Plastic, Reconstructive and Aesthetic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
⁴ Department of Infectious Diseases, Chiba University Hospital, Chiba, Japan.
⁵ Department of Dermatology, Gunma University Graduate School of Medicine, Gunma, Japan.
⁶ Department of Orthopedic surgery, Nara Medical University, Nara, Japan.
⁷ Department of Health Development and Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
⁸ Department of Endocrinology, Hematology and Gerontology, Chiba University Graduate School of Medicine, Chiba, Japan.
⁹ Center for the Promotion of Clinical Investigation, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.
¹⁰ Department of Community Healthcare & Geriatrics, Nagoya University Graduate School of Medicine, Institutes of Innovation for Future Society, Nagoya University, Nagoya, Japan.

PMID: 33258561
DOI: 10.1111/ggi.14095

Abstract

For the purpose of examining the characteristics of dyslipidemia and fatty liver in patients with Werner syndrome in Japan in recent years, we searched all case reports of Japanese Werner syndrome reported on Medical Online and PubMed since 1996, and collected and examined the data and clinical features described in these reports. In addition, as there are few descriptions of treatment methods in these reports from Medical Online and PubMed, we analyzed 12 cases for which detailed data on treatment methods are available at Chiba University. Geriatr Gerontol Int 2021; 21: 133-138.

Keywords: Werner syndrome; clinical medicine; geriatric medicine; management guideline.

MeSH terms

Dyslipidemias* / diagnosis
Fatty Liver*
Humans
Japan
Werner Syndrome Helicase
Werner Syndrome*

Substances

Werner Syndrome Helicase