Fecal Microbiota Transplants Annually and Their Positive Clinical Impact

Clin Transl Gastroenterol. 2020 Nov;11(11):e00247. doi: 10.14309/ctg.0000000000000247.


Introduction: Although fecal microbiota transplantation (FMT) is a recommended, clinically efficacious, and cost-effective treatment for recurrent Clostridioides difficile infection (CDI), the scale of FMT use in the United States is unknown.

Methods: We developed a population-level CDI model.

Results: We estimated that 48,000 FMTs could be performed annually, preventing 32,000 CDI recurrences.

Discussion: Improving access to FMT could lead to tens of thousands fewer C. difficile episodes per year.

Publication types

  • Research Support, Non-U.S. Gov't