Clinical Implications of Removing Race From Estimates of Kidney Function

JAMA. 2021 Jan 12;325(2):184-186. doi: 10.1001/jama.2020.22124.


This study uses NHANES data to compare estimated glomerular filtration rate from serum creatinine (eGFRcr) values calculated with vs without race as a variable, and to estimate the number of patients for whom nephrologist referrals and drug and renal replacement recommendations would change as a result according to KDIGO guidelines and Medicare benefit policies.

MeSH terms

  • Adult
  • African Americans*
  • Algorithms
  • Creatinine / blood*
  • Female
  • Glomerular Filtration Rate*
  • Humans
  • Kidney / physiopathology*
  • Male
  • Nutrition Surveys
  • Racial Groups*
  • Renal Insufficiency, Chronic / blood
  • Renal Insufficiency, Chronic / diagnosis*
  • Renal Insufficiency, Chronic / physiopathology


  • Creatinine