USA stockpiling of remdesivir: How should the world respond?

J Comp Eff Res. 2020 Dec;9(18):1243-1246. doi: 10.2217/cer-2020-0174. Epub 2020 Dec 4.


The race to find an effective treatment for coronavirus disease 2019 (COVID-19) is still on, with only two treatment options currently authorized for emergency use and/or recommended for patients hospitalized with severe respiratory symptoms: low-dose dexamethasone and remdesivir. The USA decision to stockpile the latter has resulted in widespread condemnation and in similar action being taken by some other countries. In this commentary we discuss whether stockpiling remdesivir is justified in light of the currently available evidence.

Keywords: COVID-19; SARS-CoV-2; antiviral; coronavirus; dexamethasone; remdesivir; stockpiling.

Publication types

  • Review

MeSH terms

  • Adenosine Monophosphate / analogs & derivatives*
  • Adenosine Monophosphate / therapeutic use
  • Alanine / analogs & derivatives*
  • Alanine / therapeutic use
  • Antiviral Agents / therapeutic use*
  • COVID-19 Drug Treatment*
  • Humans
  • International Cooperation*
  • Internationality*
  • SARS-CoV-2
  • Strategic Stockpile / methods*
  • United States


  • Antiviral Agents
  • remdesivir
  • Adenosine Monophosphate
  • Alanine