Two new phenolic glucosides from marine-derived fungus Aspergillus sp

Nat Prod Res. 2022 Jul;36(13):3255-3261. doi: 10.1080/14786419.2020.1851226. Epub 2020 Dec 8.


Two new phenolic glucosides, including a new O-glycoside (1) and a new C-glycoside (2), were isolated from a marine-derived fungus Aspergillus sp. The structures of new compounds were elucidated through interpretations of spectroscopic evidence and high-resolution electrospray ionization mass spectrometry. The hexose unit of 1 was identified as β-D-glucose by comparison with an authentic sample via HPLC after acid hydrolysis and derivatization. All compounds were evaluated for their ability to inhibit LPS-induced NO production in RAW264.7 macrophages, but none of them displayed significant activity.

Keywords: Aspergillus sp; glucoside; phenolic.

MeSH terms

  • Aspergillus* / chemistry
  • Fungi
  • Glucosides* / chemistry
  • Glycosides / chemistry
  • Phenols / pharmacology


  • Glucosides
  • Glycosides
  • Phenols