Multiple testing: when is many too much?

Eur J Endocrinol. 2021 Mar;184(3):E11-E14. doi: 10.1530/EJE-20-1375.

Abstract

In almost all medical research, more than a single hypothesis is being tested or more than a single relation is being estimated. Testing multiple hypotheses increases the risk of drawing a false-positive conclusion. We briefly discuss this phenomenon, which is often called multiple testing. Also, methods to mitigate the risk of false-positive conclusions are discussed.

Publication types

  • Editorial

MeSH terms

  • Biomedical Research*
  • False Positive Reactions*
  • Humans
  • Research Design*