Fatal SARS-CoV-2 infection in a male patient with Good's syndrome

Clin Immunol. 2021 Feb:223:108644. doi: 10.1016/j.clim.2020.108644. Epub 2020 Dec 8.

Abstract

  1. •

    This study describes for the first time the clinical course of SARS-CoV-2 infection in a male patient with Good's syndrome.

  2. •

    Absence of peripheral B cells may not always correlate with mild clinical course of COVID-19.

  3. •

    Immunological findings in COVID-19 may not apply to all clnical settings in the same manner.

Keywords: COVID-19; Good's sydrome (GS); SARS-CoV-2.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Agammaglobulinemia / diagnosis*
  • B-Lymphocytes / immunology*
  • COVID-19 / diagnosis*
  • Continuous Positive Airway Pressure
  • Fatal Outcome
  • Humans
  • Immunologic Deficiency Syndromes / diagnosis*
  • Lung / diagnostic imaging*
  • Male
  • Middle Aged
  • Myasthenia Gravis / diagnosis*
  • SARS-CoV-2 / physiology*
  • T-Lymphocytes / immunology*
  • Thymoma / diagnosis*
  • Thymus Neoplasms / diagnosis*
  • Tomography, X-Ray Computed