Pulmonary sequestration: What the radiologist should know

Clin Imaging. 2021 May:73:61-72. doi: 10.1016/j.clinimag.2020.11.040. Epub 2020 Dec 3.

Abstract

Pulmonary sequestration consists of a nonfunctioning mass of lung tissue, either sharing the pleural envelope of the normal lung (intralobar) or with its own pleura (extralobar), lacking normal communication with the tracheobronchial tree and receiving its arterial supply by one or more systemic vessels. It is the second most common congenital lung anomaly according to pediatric case series, but its real prevalence is likely to be underestimated, and imaging plays a key role in the diagnosis and treatment management of the condition and its potential complications. We will give a brief overview of the pathophysiology, clinical presentation and imaging findings of intra- and extralobar pulmonary sequestration, with particular reference to multidetector computed tomography as part of a powerful and streamlined diagnostic approach.

Keywords: Diagnostic imaging; Extralobar pulmonary sequestration; Intralobar pulmonary sequestration; Therapeutic embolization.

Publication types

  • Review

MeSH terms

  • Bronchi
  • Bronchopulmonary Sequestration* / diagnostic imaging
  • Child
  • Humans
  • Lung / diagnostic imaging
  • Pleura
  • Radiologists