Pulmonary and intracranial miliary tuberculosis secondary to Behçet's anti-TNF alfa treatment

Asmae Sekkat; Siham Bouchal; Yahya Charifi; Khalid El Hajjam; Youssef Lamrani Alaoui; Mohammed Faouzi Belahsen; Mustapha Maaroufi; Badr Alami

doi:10.1016/j.radcr.2020.11.029

Pulmonary and intracranial miliary tuberculosis secondary to Behçet's anti-TNF alfa treatment

Radiol Case Rep. 2020 Dec 4;16(2):338-342. doi: 10.1016/j.radcr.2020.11.029. eCollection 2021 Feb.

Authors

Asmae Sekkat¹, Siham Bouchal², Yahya Charifi¹, Khalid El Hajjam¹, Youssef Lamrani Alaoui¹, Mohammed Faouzi Belahsen², Mustapha Maaroufi¹, Badr Alami¹

Affiliations

¹ Radiology department, Hassan II University Hospital, Fez, Morocco.
² Neurology department, Hassan II University Hospital, Fez, Morocco.

Abstract

Behçet disease is a rare vasculitis that affects vessels of different body parts, causing different kinds of manifestations. We report a case of a 47 years old woman who had a tumor necrosis factor alfa blocker prescription due to a Behçet's disease relapse. The patient then developed a cerebral and pulmonary tuberculous miliary due to immunodeficiency. The aim of this work is to show that tuberculosis infection is a common complication of the administration of tumor necrosis factor alfa blocker, and the importance to perform a tuberculosis screening before starting the treatment.

Keywords: Anti-TNF alfa; Behçet's disease; Immunodeficiency; Miliary; Tuberculosis.

Publication types

Case Reports