A computational investigation of strain concentration in the brain in response to a rapid temperature rise

J Mech Behav Biomed Mater. 2021 Mar:115:104228. doi: 10.1016/j.jmbbm.2020.104228. Epub 2020 Dec 5.

Abstract

Following the mysterious health attacks on U.S. diplomats in Cuba in 2016, the cause of concussion-like symptoms concurrent with strange noises heard by the diplomats remains undetermined. A wide range of possible causes of the sensations have been proposed: pulsed microwave exposure, infrasound acoustic devices, pesticides/neurotoxins, and even mass hysteria (psychogenic illness). Here, we numerically examine the pulsed microwave exposure hypothesis and the simulated mechanical response of brain tissue. A computational model is used to examine the influence of various spatially varying temperature gradients and pulse durations on the mechanical response of brain tissue. We show that a stress-focusing effect due to a rapid temperature increase may result in brain tissue strains larger than the initially applied thermal strains.

Keywords: Pulsed high power microwave bioeffects; Thermal expansion and mechanics of brain tissue; Traumatic brain injury (TBI).

MeSH terms

  • Brain Concussion*
  • Brain*
  • Humans
  • Microwaves
  • Temperature