The clinical characteristics and subtypes of patients with cognitive impairment in memory clinic

J Clin Neurosci. 2020 Dec;82(Pt A):186-191. doi: 10.1016/j.jocn.2020.10.031. Epub 2020 Nov 20.

Abstract

To explore the demographic characteristics and main types of memory impairment in the Memory Clinic of China and to provide references for future research. Demographic, cognitive, and etiological data of 2,742 cognitive impairment (CI) patients who were in the Memory Clinic at Tianjin Huanhu Hospital from January 2011 to October 2018 were analyzed. The main subtypes of CI were AD (38.33%), MCI (19.55%), VaD (8.57%), FTLD (7.37%) and DLB/PDD (5.91%). The mean age was 68.5 ± 9.97, with 82.13% older than 60 years. There were slightly more females (50.58%) than males (49.42%). There were a relatively equal number of patients who were educated less than (55.12%) and more than nine years (44.88%). Most patients (82.91%) were married and only 23.63% patients had a family history of CI. CI occurred primarily in the elderly, namely those who were between 60 and 79 years old. More than half of those with AD, DLB, PDD, and FTLD were categorized at mild or moderate levels. The bvFTD (n = 127, 62.9%) was the primary subtype of FTLD. Standardized diagnostic procedures, detailed neuropsychological assessments, molecular biology tests, and follow-ups are important for the early diagnosis and treatment of cognitive impairment diseases.

Keywords: Cognitive impairment; Dementia; Memory clinic.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease
  • China
  • Cognition Disorders / diagnosis
  • Cognitive Dysfunction / epidemiology*
  • Cognitive Dysfunction / psychology*
  • Female
  • Humans
  • Lewy Body Disease
  • Male
  • Memory Disorders
  • Middle Aged
  • Neuropsychological Tests