Pallidotomy for Dystonia

Neurol India. 2020 Nov-Dec;68(Supplement):S322-S324. doi: 10.4103/0028-3886.302460.


Background: Deep brain stimulation (DBS) is currently the preferred surgical treatment for various movement disorders. Pallidotomy is an effective procedure for patients with dystonia and Parkinson's disease and was the surgical treatment of choice before the advent of DBS. However, it can be the preferred modality in immunocompromised patients and those patients who cannot afford DBS due to financial constraints. Hypophonia, dysarthria and dysphagia are the most significant complications of bilateral pallidotomy.

Objective: The aim of this study was to present the surgical technique and nuances involved in bilateral simultaneous pallidotomy in a patient with generalized dystonia.

Procedure: A 30-year male with primary generalized dystonia presented to us with preoperative Burke-Fahn-Marsden (BFM) Dystonia Rating Scale of 24. After acquiring preoperative volumetric 3T MRI and stereotactic CT, bilateral pallidotomy was done under general anesthesia. There were no procedure related complications.

Results: At two months of follow-up, his BFM dystonia score improved from 24 to 4.5.

Conclusion: Appropriately acquired volumetric MRI, meticulous planning and meticulously performed surgical procedure can help in achieving good outcome and minimize the complications.

Keywords: Deep brain stimulation; Pallidotomy; dystonia; operative nuances; radiofrequency.

MeSH terms

  • Deep Brain Stimulation*
  • Dystonia* / surgery
  • Dystonic Disorders* / surgery
  • Globus Pallidus / surgery
  • Humans
  • Male
  • Movement Disorders*
  • Pallidotomy*
  • Treatment Outcome