Impact of COVID-19 in solid organ transplant recipients

Am J Transplant. 2021 Mar;21(3):925-937. doi: 10.1111/ajt.16449. Epub 2021 Feb 26.

Abstract

The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exploded onto the world stage in early 2020. The impact on solid organ transplantation (SOT) has been profound affecting potential donors, candidates, and recipients. Importantly, decreased donations and the pressure of limited resources placed on health care by the pandemic also disrupted transplant systems. We address the impact of COVID-19 on organ transplantation globally and review current understanding of the epidemiology, outcomes, diagnosis, and treatment of COVID-19 in SOT recipients.

Keywords: COVID-19; United infection and infectious agents - viral; antibiotic: antiviral; health services and outcomes research viewpoint; immunosuppression / immune modulation; infectious disease; organ procurement; organ transplantation in general.

Publication types

  • Review

MeSH terms

  • COVID-19 / epidemiology*
  • Comorbidity
  • Humans
  • Organ Transplantation / trends*
  • Pandemics*
  • SARS-CoV-2*
  • Tissue Donors / supply & distribution*
  • Tissue and Organ Procurement / methods*
  • Transplant Recipients / statistics & numerical data*