Tellurium(II)/Tellurium(III)-Catalyzed Cross-Dehydrogenative C-N Bond Formation

Christopher Cremer; Monalisa Goswami; Christian K Rank; Bas de Bruin; Frederic W Patureau

doi:10.1002/anie.202015248

Tellurium(II)/Tellurium(III)-Catalyzed Cross-Dehydrogenative C-N Bond Formation

Angew Chem Int Ed Engl. 2021 Mar 15;60(12):6451-6456. doi: 10.1002/anie.202015248. Epub 2021 Feb 4.

Authors

Christopher Cremer¹, Monalisa Goswami², Christian K Rank¹, Bas de Bruin³, Frederic W Patureau¹

Affiliations

¹ Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.
² Spark904 BV, Science Park 400, 1098 XH, Amsterdam, The Netherlands.
³ Van't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands.

Abstract

The Te^II /Te^III -catalyzed dehydrogenative C-H phenothiazination of challenging phenols featuring electron-withdrawing substituents under mild aerobic conditions and with high yields is described. These unexpected Te^II /Te^III radical catalytic properties were characterized by cyclic voltammetry, EPR spectroscopy, kinetic experiments, and DFT calculations.

Keywords: dehydrogenative C−N bond formation; radical catalyst; selenium heterocycle; tellurium catalysis.; tellurium heterocycle.

Abstract

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