Does Prostate-Specific Membrane Antigen Avidity of Vertebral Hemangioma Change?

Clin Nucl Med. 2021 Mar 1;46(3):229-230. doi: 10.1097/RLU.0000000000003457.


Vertebral hemangiomas are the most common benign tumors of the spine and mostly occur in the thoracic spine. Mostly they are detected incidentally during imaging studies for other reasons. We present the case of vertebral hemangioma that showed prostate-specific membrane antigen uptake in the second 68Ga-prostate-specific membrane antigen PET/CT, whereas no uptake was observed in the initial study.

Publication types

  • Case Reports

MeSH terms

  • Antigens, Surface / metabolism*
  • Glutamate Carboxypeptidase II / metabolism*
  • Hemangioma / diagnostic imaging
  • Hemangioma / metabolism*
  • Humans
  • Male
  • Positron Emission Tomography Computed Tomography
  • Spinal Neoplasms / diagnostic imaging
  • Spinal Neoplasms / metabolism*


  • Antigens, Surface
  • FOLH1 protein, human
  • Glutamate Carboxypeptidase II