Polycystic Ovarian Syndrome and Fertility

Jessica A Lentscher; Breonna Slocum; Saioa Torrealday

doi:10.1097/GRF.0000000000000595

Polycystic Ovarian Syndrome and Fertility

Clin Obstet Gynecol. 2021 Mar 1;64(1):65-75. doi: 10.1097/GRF.0000000000000595.

Authors

Jessica A Lentscher^{1

2}, Breonna Slocum³, Saioa Torrealday¹

Affiliations

¹ Walter Reed National Military Medical Center.
² Program of Reproductive Endocrinology and Infertility, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
³ Department of Obstetrics and Gynecology, Georgetown University, Washington, District of Columbia.

PMID: 33337743
DOI: 10.1097/GRF.0000000000000595

Abstract

Polycystic ovary syndrome (PCOS) is a common endocrinopathy that has been associated with impaired fertility. This chapter reviews the underlying pathophysiology of PCOS and the associated fertility barriers of the condition. Psychologic concerns, hypothalamic-pituitary, ovarian, and mitochondria dysfunction, obesity, and the role of vitamin D in PCOS are considered with respect to fertility. Lastly, pregnancy risk factors associated with PCOS are also reviewed.

MeSH terms

Female
Fertility
Humans
Obesity / complications
Polycystic Ovary Syndrome* / complications
Pregnancy
Vitamin D

Substances

Vitamin D