Visual experience dependent plasticity in humans

Curr Opin Neurobiol. 2021 Apr:67:155-162. doi: 10.1016/j.conb.2020.11.011. Epub 2020 Dec 16.


While sensitive periods in brain development have often been studied by investigating the recovery of visual functions after a congenital phase of visual deprivation in non-human animals, research in humans who had recovered sight after a transient phase of congenital blindness is still scarce. Here, we discuss the hypothesis put forward based on non-human primate work which states that the effects of experience increase downstream the visual processing hierarchy. Recent results from behavioral and neuroscience studies in sight recovery individuals are discussed in the context of research findings from permanently congenitally blind humans as well as from prospective studies in infants and children.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Blindness*
  • Humans
  • Neuronal Plasticity
  • Prospective Studies
  • Vision, Ocular
  • Visual Perception*