Recent case studies on the use of ozone to combat coronavirus: Problems and perspectives

Soumya Nagashri Manjunath; M Sakar; Manmohan Katapadi; R Geetha Balakrishna

doi:10.1016/j.eti.2020.101313

Recent case studies on the use of ozone to combat coronavirus: Problems and perspectives

Environ Technol Innov. 2021 Feb:21:101313. doi: 10.1016/j.eti.2020.101313. Epub 2020 Dec 13.

Authors

Soumya Nagashri Manjunath¹, M Sakar², Manmohan Katapadi^{1

3}, R Geetha Balakrishna²

Affiliations

¹ Ohio Heart Group, 800 East Broad Street, Columbus, OH 43205, USA.
² Centre for Nano and Material Sciences, Jain University, Bangalore 562112, Karnataka, India.
³ Ohio University, Ohio Heart Group, Ohio Health systems and Mount Carmel Health systems, 800 East Broad Street, Columbus, OH 43205, USA.

Abstract

Coronavirus pandemic has created havoc in the world. COVID-19 is now officially labeled as Severe Acute Respiratory Syndrome-related Coronavirus-SARS-CoV-2. Therefore, it is equally important to combat the virus both inside the human body as well as in the environment. These viruses, being RNA viruses, are found to be susceptible to ozone. Ozone being an unstable molecule can breakup into its split products namely reactive oxygen species and ozonides creating a toxic environment for these viruses. Ozone mainly prevents the membrane fusion with the host cell, thus interfering with their replication. With vast applications of the gas, it has created a new spark in the field of medicine in combating these viruses and many other organisms. In this context, this article provides insights from recent clinical and research studies on the problems and possibilities in employing the ozone to combat the coronaviruses.

Keywords: Anti-viral therapeutics; COVID-19; Coronavirus; Ozone therapy; SARS-coV-2.