Gender medicine: the impact of probiotics on male patients

Clin Ter. 2021 Jan-Feb;171(1):e8-e15. doi: 10.7417/CT.2021.2274.


Purpose: Numerous studies in the literature confirm the importance of the use of probiotics in inflammatory states of the prostate in humans. Our pilot study aimed to test probiotics strains ability to improve urinary bacterial load in male subjects.

Methods: Twenty healthy men aged 55-65 years, with recurrent urinatory infections were enrolled and randomized into 2 groups. Urine culturing to detect Enterobacteriaceae (Escherichia Coli and Enterococcus faecalis) was performed at baseline and at 12 weeks after the starting of the study.

Results: We found that taking the probiotic reduces the bacterial load of E. coli and E. faecalis in urine cultures. The use of the probiotic in these inflammatory states does not affect the change in weight in the tested subjects.

Conclusions: Our data confirm and improve the main results reported in the scientific literature on the importance of taking probiotics in prostatitis.

Keywords: Gender medicine; Probiotics; Wellbeing.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Double-Blind Method
  • Enterococcus faecalis / isolation & purification*
  • Escherichia coli / isolation & purification*
  • Humans
  • Male
  • Men's Health
  • Middle Aged
  • Pilot Projects
  • Probiotics / therapeutic use*
  • Prostatitis / drug therapy*
  • Prostatitis / urine*