Dose-response for yttrium-90 resin microsphere radioembolisation

Nucl Med Commun. 2021 Mar 1;42(3):345-347. doi: 10.1097/MNM.0000000000001351.


The fundamental premise of yttrium-90 radioembolisation is to balance safety with efficacy. To achieve this, dose-response guidance must be provided. This is a tabulation of published data of key dose-response metrics for yttrium-90 resin microsphere radioembolisation of liver malignancies. Metrics are expressed in terms of mean radiation absorbed doses (Gy), dose-volume histograms, Biologically Effective Doses, Normal Tissue Complication Probability and Tumour Control Probability.

MeSH terms

  • Carcinoma, Hepatocellular / therapy
  • Embolization, Therapeutic*
  • Humans
  • Liver Neoplasms / therapy
  • Microspheres*
  • Radiation Dosage*
  • Radiotherapy Dosage
  • Resins, Synthetic / chemistry*
  • Yttrium Radioisotopes / chemistry*
  • Yttrium Radioisotopes / therapeutic use*


  • Resins, Synthetic
  • Yttrium Radioisotopes
  • Yttrium-90