Fatal neurotoxicity after chimeric antigen receptor T-cell therapy: An unexpected case of fludarabine-associated progressive leukoencephalopathy

Eur J Cancer. 2021 Feb:144:178-181. doi: 10.1016/j.ejca.2020.11.021. Epub 2020 Dec 23.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antineoplastic Agents / adverse effects
  • Fatal Outcome
  • Humans
  • Immunotherapy, Adoptive / adverse effects*
  • Leukoencephalopathies / chemically induced
  • Leukoencephalopathies / pathology*
  • Lymphoma, Large B-Cell, Diffuse / immunology
  • Lymphoma, Large B-Cell, Diffuse / pathology
  • Lymphoma, Large B-Cell, Diffuse / therapy*
  • Male
  • Neurotoxicity Syndromes / etiology
  • Neurotoxicity Syndromes / pathology*
  • Retroperitoneal Neoplasms / immunology
  • Retroperitoneal Neoplasms / pathology
  • Retroperitoneal Neoplasms / therapy*
  • Vidarabine / adverse effects
  • Vidarabine / analogs & derivatives*

Substances

  • Antineoplastic Agents
  • Vidarabine
  • fludarabine