Challenges in the management of acute intermittent porphyria with recurrent attacks during pregnancy: A case report

Daphne Vassiliou; Chariklia Lempessi; Pauline Harper; Eliane Sardh

doi:10.1002/ccr3.3185

Challenges in the management of acute intermittent porphyria with recurrent attacks during pregnancy: A case report

Clin Case Rep. 2020 Jul 30;8(12):2483-2487. doi: 10.1002/ccr3.3185. eCollection 2020 Dec.

Authors

Daphne Vassiliou^{1

2

3}, Chariklia Lempessi⁴, Pauline Harper^{2

5}, Eliane Sardh^{1

2

3}

Affiliations

¹ Department of Endocrinology and Nephrology, Inflammation and Infection Karolinska University Hospital Stockholm Sweden.
² Centre for Inherited Metabolic Diseases (CMMS) Porphyria Centre Sweden Karolinska University Hospital Stockholm Sweden.
³ Department of Molecular Medicine and Surgery Karolinska Institutet Stockholm Sweden.
⁴ Department of Medicine Örebro University Hospital Örebro Sweden.
⁵ Department of Medical Biochemistry and Biophysics Karolinska Institutet Stockholm Sweden.

Abstract

In cases of recurrent attacks of acute porphyria during pregnancy, prophylactic administration of heme arginate should be considered. Clinical and biochemical monitoring of the disease and a close collaboration with a porphyria center are crucial.

Keywords: Acute intermittent porphyria; case report; heme arginate; pregnancy.

Publication types

Case Reports