Trimethoprim-induced drug reaction with eosinophilia and systemic symptoms (DRESS) associated with reactivation of human herpes virus-6 (HHV-6) leading to acute liver failure

Clin Case Rep. 2020 Aug 9;8(12):2568-2573. doi: 10.1002/ccr3.3218. eCollection 2020 Dec.

Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome can have insidious symptoms which may lead to acute liver failure and death. Prompt recognition, stopping offending drug, and initiating corticosteroid are the mainstay of treatment. Early involvement of a specialist liver unit is vital.

Keywords: acute liver failure; drug reaction with eosinophilia and systemic symptoms; drug‐induced liver injury; human herpes virus‐6; jaundice; liver transplant.

Publication types

  • Case Reports