Diagnostic challenges in an aggressive case of peripheralizing marginal zone lymphoma

Sujal I Shah; Christopher R D'Angelo; Jeremy D Kratz; David T Yang

doi:10.1002/ccr3.3395

Diagnostic challenges in an aggressive case of peripheralizing marginal zone lymphoma

Clin Case Rep. 2020 Oct 18;8(12):3303-3310. doi: 10.1002/ccr3.3395. eCollection 2020 Dec.

Authors

Sujal I Shah¹, Christopher R D'Angelo², Jeremy D Kratz², David T Yang¹

Affiliations

¹ Department of Pathology University of Wisconsin School of Medicine and Public Health Madison WI USA.
² Department of Medicine Section of Hematology/Oncology University of Wisconsin School of Medicine and Public Health Madison WI USA.

Abstract

B-cell lymphomas with atypical presentation or immunophenotype pose diagnostic challenges. Conventional ancillary tests (cytogenetics, FISH) can help, but have technical limitations. New technologies such as mate-pair sequencing (MPSeq) offer a route around these technical limitations.

Keywords: B‐cell lymphoma; cytogenetics; mate‐pair sequencing; splenic marginal zone lymphoma; t(2;7).

Publication types

Case Reports

Abstract

Publication types

Grants and funding