Acute Hematogenous Osteomyelitis in Children: Clinical Presentation and Management

Infect Drug Resist. 2020 Dec 14:13:4459-4473. doi: 10.2147/IDR.S257517. eCollection 2020.

Abstract

Acute hematogenous osteomyelitis (AHO) is a common invasive infection encountered in the pediatric population. In addition to the acute illness, AHO has the potential to create long-term morbidity and functional limitations. While a number of pathogens may cause AHO, Staphylococcus aureus is the most common organism identified. Despite the frequency of this illness, little high-quality data exist to guide providers in the care of these patients. The literature is reviewed regarding the epidemiology, microbiology and management of AHO in children. A framework for empiric therapy is provided drawing from the available literature and published guidelines.

Keywords: Staphylococcus aureus; oral antibiotics; osteomyelitis; pediatrics.

Publication types

  • Review