Characterization and phylogenetic analysis of the complete mitochondrial genome of the human pathogenic fungus Cryptococcus sp. (Tremellales: Cryptococcaceae)

Yue Chen; Xiaorong Sun; Wenjuan Gui; Qianru Zhang; Dan Su

doi:10.1080/23802359.2019.1693295

Characterization and phylogenetic analysis of the complete mitochondrial genome of the human pathogenic fungus Cryptococcus sp. (Tremellales: Cryptococcaceae)

Mitochondrial DNA B Resour. 2019 Nov 21;4(2):4200-4201. doi: 10.1080/23802359.2019.1693295.

Authors

Yue Chen¹, Xiaorong Sun¹, Wenjuan Gui², Qianru Zhang^{3

4

5

6}, Dan Su¹

Affiliations

¹ Chengdu Bio-HT Company Limited, Chengdu, China.
² General Hospital of Ningxia Medical University, Yinchuan, China.
³ West China School of Public Health and West China Fourth Hospital, Healthy Food Evaluation Research Center, Sichuan University, Chengdu, China.
⁴ State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
⁵ Guangdong Raynovent Biotech Co., Ltd., Guangdong, China.
⁶ Guangdong Zhongsheng Pharmaceutical Co., Ltd., Guangdong, China.

Abstract

In the present study, the complete mitogenome of Cryptococcus sp. were sequenced and assembled. The complete mitogenome of Cryptococcus sp. was composed of circular DNA molecules, with a total length of 30,029 bp. The base composition of this mitochondrial genome is as follows: A (31.94%), T (34.89%), G (15.97%), and C (17.21%). The mitogenome contains 20 protein-coding genes, 2 ribosomal RNA genes (rRNA), and 22 transfer RNA (tRNA) genes. Phylogenetic analysis showed that the mitogenome of the Cryptococcus sp. exhibited a closest relationship with Cryptococcus gattii.

Keywords: Cryptococcus; mitochondrial genome; phylogenetic analysis.