Role of thuja in the management of laryngeal papilloma

BMJ Case Rep. 2020 Dec 22;13(12):e238846. doi: 10.1136/bcr-2020-238846.

Abstract

Juvenile respiratory laryngeal papillomatosis is a subset of a larger clinical entity of recurrent respiratory papillomatosis. It is characterised by the development of recurrent papillomata in the vocal folds. Human papillomavirus types 6 and 11 has been implicated to be the most common strain of virus associated with the formation of laryngeal papilloma. Clinical diagnosis is based on typical appearance of warty lesion on endoscopy. Surgery is the primary line of management along with adjuvant therapy like antiviral drugs and immunomodulators. Thuja occidentalis is a tree native to North America whose leaves and leaf oil have antiviral, antibacterial and antifungal properties. It has been widely used for the treatment of condylomatous skin lesions and warts. Here we discuss the outcome of thuja as an adjuvant therapy in the treatment of laryngeal papillomatosis in an 8-year-old child.

Keywords: ear; human papilloma virus; nose and throat.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • Chemotherapy, Adjuvant / methods
  • Child
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Humans
  • Laryngeal Neoplasms / diagnosis
  • Laryngeal Neoplasms / pathology
  • Laryngeal Neoplasms / therapy*
  • Laryngoscopy
  • Larynx / diagnostic imaging
  • Larynx / pathology
  • Larynx / surgery
  • Male
  • Neoplasm Recurrence, Local / diagnosis
  • Neoplasm Recurrence, Local / therapy*
  • Papilloma / diagnosis
  • Papilloma / pathology
  • Papilloma / therapy*
  • Plant Extracts / administration & dosage*
  • Reoperation
  • Thuja / chemistry*
  • Tracheostomy*
  • Treatment Outcome

Substances

  • Plant Extracts

Supplementary concepts

  • Laryngeal papillomatosis