Uncommon presentation of allergic bronchopulmonary aspergillosis during the COVID-19 lockdown: a case report

BMC Pulm Med. 2020 Dec 29;20(1):325. doi: 10.1186/s12890-020-01373-7.


Background: During the ongoing pandemic of coronavirus disease 2019 (COVID-19), lockdown periods have changed the way that people and communities live, work and interact.

Case presentation: This case report describes an uncommon but important presentation of allergic bronchopulmonary aspergillosis (ABPA) in a previously healthy male, who decided to live in the basement of his house when Italy entered a nationwide lockdown during the COVID-19 pandemic. As high resolution computed tomography (HRCT) of the chest on admission showed diffuse miliary nodules, a miliary tuberculosis was initially suspected. However, further investigations provided a diagnosis of unusual presentation of ABPA.

Conclusions: This case highlights the importance of maintaining awareness of Aspergillus-associated respiratory disorders during the COVID-19 pandemic, especially because lifestyle changes associated with home isolation carry an increased risk of exposure to mold spores present in some indoor environments.

Keywords: Allergic bronchopulmonary aspergillosis (ABPA); Aspergillus-associated respiratory disorders; Coronavirus disease 2019 (COVID-19).

Publication types

  • Case Reports

MeSH terms

  • Aspergillosis, Allergic Bronchopulmonary / diagnosis*
  • Aspergillosis, Allergic Bronchopulmonary / diagnostic imaging
  • COVID-19 / diagnosis*
  • COVID-19 / prevention & control
  • Communicable Disease Control
  • Diagnosis, Differential
  • Humans
  • Italy
  • Male
  • Middle Aged
  • SARS-CoV-2
  • Tomography, X-Ray Computed
  • Tuberculosis, Miliary / diagnosis*