Radiation Necrosis of the Lateral Skull Base and Temporal Bone

Semin Plast Surg. 2020 Nov;34(4):265-271. doi: 10.1055/s-0040-1721763. Epub 2020 Dec 24.

Abstract

Radiation therapy plays a critical role in the treatment of malignancies involving the head and neck. Although the therapeutic effects of ionizing radiation are achieved, normal tissues are also susceptible to injury and significant long-term sequelae. Osteoradionecrosis of the temporal bone (ORNTB) is among the many complications that can arise after therapy. ORNTB is a debilitating and potentially lethal condition that continues to challenge patients and treating physicians. Herein, we review the pathophysiology, presentation, work-up, and management of ORNTB.

Keywords: head and neck cancer; osteoradionecrosis; reconstructive surgery; temporal bone cancer.

Publication types

  • Review