Colorimetric sensing of chloride in sweat based on fluorescence wavelength shift via halide exchange of CsPbBr3 perovskite nanocrystals

Mikrochim Acta. 2021 Jan 2;188(1):2. doi: 10.1007/s00604-020-04653-5.

Abstract

Considering the high importance of the rapid detection of chloride ion (Cl-) in sweat for the diagnosis of fibrotic cysts, we have investigated the heterogeneous halide exchange between CsPbBr3 perovskite nanocrystals (PNCs) in n-hexane and Cl- in aqueous solution. The results show that CsPbBr3 PNCs could achieve fast halide exchange with Cl- in the aqueous phase under magnetic stirring at pH = 1, accompanied by a significant wavelength blue shift and vivid fluorescence color changes from green to blue. Therefore, a fluorescence wavelength shift-based colorimetric sensing of Cl- based on the halide exchange of CsPbBr3 PNCs has been developed to realize the rapid detection of Cl- in sweat. Compared with the conventional fluorescence intensity-based method, this method is of high convenience since the whole procedure could be achieved within 5 min without any sample pretreatment (even no dilution), demonstrating promising application prospects. Graphical Abstract Fluorescence wavelength-shift based colorimetric sensing of chloride in sweat via halide exchange of CsPbBr3 perovskite nanocrystals.

Keywords: Chloride determination; Colorimetric sensing; CsPbBr3 perovskite nanocrystals; Fluorescence wavelength shift; Halide exchange.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bromides / chemistry
  • Cesium / chemistry
  • Chlorides / analysis*
  • Colorimetry / methods
  • Fluorescent Dyes / chemistry*
  • Humans
  • Lead / chemistry
  • Nanoparticles / chemistry*
  • Spectrometry, Fluorescence / methods
  • Sweat / chemistry*

Substances

  • Bromides
  • Chlorides
  • Fluorescent Dyes
  • Cesium
  • Lead