Large-scale production of enzymes for biotechnology uses

Curr Opin Biotechnol. 2021 Jun;69:68-76. doi: 10.1016/j.copbio.2020.12.002. Epub 2020 Dec 31.


Enzymes are biocatalysts that speed up the chemical reaction to obtain the final valuable product/s. Biotechnology has revolutionized the use of traditional enzymes to be applicable in industries such as food, beverage, personal and household care, agriculture, bioenergy, pharmaceutical, and various other segments. With respect to the exponential growth of enzymes in biotech industries, it becomes important to highlight the advancements and impact of enzyme technology over recent years. In this review article, we discuss the existing and emerging production approaches, applications, developments, and global need for enzymes. Special emphasis is given to the predominantly utilized hydrolytic microbial enzymes in industrial bioprocesses.

Publication types

  • Review

MeSH terms

  • Biotechnology*
  • Enzymes
  • Industry*


  • Enzymes