Abstract
Lithium tremor worsened in two patients when caffeine (coffee) was eliminated from their diets. An associated reduction in renal lithium clearance resulting in increased serum lithium level is thought to be the mechanism.
MeSH terms
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Adult
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Bipolar Disorder / drug therapy
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Caffeine / adverse effects*
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Caffeine / pharmacology
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Coffee*
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Female
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Humans
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Lithium / administration & dosage
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Lithium / adverse effects*
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Lithium / metabolism
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Middle Aged
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Substance Withdrawal Syndrome / metabolism*
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Tremor / chemically induced*