A novel mouse model of hyperuricemia expressing a human functional ABCG2 variant

Kidney Int. 2021 Jan;99(1):12-14. doi: 10.1016/j.kint.2020.10.021.

Authors

Anna Köttgen¹, Michael Köttgen²

Affiliations

¹ Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany. Electronic address: anna.koettgen@uniklinik-freiburg.de.
² Department of Medicine, Renal Division, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

PMID: 33390224
DOI: 10.1016/j.kint.2020.10.021

No abstract available

Keywords: ABCG2; Q141K; excretion; gout; serum urate.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

ATP Binding Cassette Transporter, Subfamily G, Member 2 / genetics
Gout*
Humans
Hyperuricemia* / genetics
Mice
Neoplasm Proteins / metabolism
Uric Acid

Substances

ABCG2 protein, human
ATP Binding Cassette Transporter, Subfamily G, Member 2
Neoplasm Proteins
Uric Acid