Dyslipidemia in childhood and adolescence: from screening to management

Curr Opin Endocrinol Diabetes Obes. 2021 Apr 1;28(2):152-158. doi: 10.1097/MED.0000000000000607.

Abstract

Purpose of review: To summarize types of dyslipidemia frequently encountered during childhood and adolescence, with a focus on screening, diagnosis, and management.

Recent findings: It is important that screening for atherosclerotic cardiovascular disease (ASCVD) begin in childhood. Genetic testing allows for increased awareness of dyslipidemia and more targeted intervention. Pharmacologic treatment of pediatric dyslipidemias has a good safety profile and can reduce adult ASCVD risk.

Summary: Much of what is known about pediatric dyslipidemia has been extrapolated from adult data, but recently, there have been increasing investigations within the pediatric population to better guide diagnosis and management of these disorders.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Atherosclerosis* / diagnosis
  • Child
  • Cholesterol, LDL
  • Dyslipidemias* / diagnosis
  • Dyslipidemias* / drug therapy
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors*
  • Mass Screening
  • Risk Factors

Substances

  • Cholesterol, LDL
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors