The prevalence of antibody to human parvovirus B19 in England and Wales

J Med Microbiol. 1988 Feb;25(2):151-3. doi: 10.1099/00222615-25-2-151.


The prevalence of antibody to human parvovirus B19 (anti-B19 IgG) in England and Wales was measured by an antibody-capture radioimmunoassay. Over 2000 sera were examined; 1422 from the general population, 374 from unselected children admitted to hospital and 300 from women attending an antenatal clinic. Waning levels of maternally-derived antibody were found in infants under 1 year old. In children 1-5 years old, 5-15% had anti-B19 IgG and this rose to 50-60% in older children, young adults and women of child-bearing age. In older people, the prevalence of anti-B19 IgG increased with age, rising to more than 85% in those over 70 years old.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Antibodies, Viral / analysis*
  • Child
  • Child, Preschool
  • England
  • Female
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Parvoviridae / immunology*
  • Radioimmunoassay
  • Wales


  • Antibodies, Viral