Impact of a motivational interviewing intervention targeting statins on adherence to concurrent hypertension or diabetes medications

Patient Educ Couns. 2021 Jul;104(7):1756-1764. doi: 10.1016/j.pec.2020.12.009. Epub 2021 Jan 2.

Abstract

Objective: This study explored if a motivational interviewing intervention customized for statins impacted adherence to concomitantly used antidiabetic/antihypertensive medications.

Methods: The intervention was conducted among patients with a history of suboptimal adherence to statins and included 152 patients in intervention and 304 controls. This retrospective study design identified patients with claims for statins and either antidiabetic/antihypertensive medications. The outcome variable was adherence, measured as proportion of days covered ≥ 0.80, to antidiabetic/antihypertensive medications. Multivariable linear and logistic regression evaluated the effect of intervention on adherence to antidiabetic/antihypertensive medications during the 6 months post-intervention.

Results: The antidiabetic group had 53 intervention patients and 102 controls. The antihypertensive group had 80 intervention patients and 159 controls. There was no significant improvement in adherence for antidiabetic/antihypertensive medications following the intervention. Adherence at baseline was a significant predictor of adherence post-intervention in the antidiabetic (OR = 6.5;P < 0.0001) and antihypertensive (OR = 4.1; P = 0.0001 & β = 0.09; P = 0.008) users. Physician specialty (OR = 3.902; P = 0.01& β = 0.09; P = 0.015) among antidiabetic users and age >70 years (OR = 2.148; P = 0.025) among antihypertensive users were predictors of adherence.

Conclusion: The intervention targeting statin did not significantly improve antihypertensive/antidiabetic adherence.

Practice implications: Targeted interventions tailored to patient past adherence and specific medications should be explored.

Keywords: Diabetes; Hyperlipidemia; Hypertension; Motivational interviewing; Proportion of days covered (PDC).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antihypertensive Agents / therapeutic use
  • Diabetes Mellitus* / drug therapy
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors* / therapeutic use
  • Hypertension* / drug therapy
  • Medication Adherence
  • Motivational Interviewing*
  • Retrospective Studies

Substances

  • Antihypertensive Agents
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors